Bromobutyl Rubber Stoppers B romobutyl Rubber Stoppers are also called
Bromobutyl Stoppers and
Bromobutyl Plug, which are commonly used to seal medicine vials and bottles for
low permeability to gases and liquids, good resistance to chemicals, weathering and ozone, etc, known as
Pharmaceutical Stoppers.
Bromobutyl Rubber Stoppers are made of Bromobutyl Rubber material. As a butyl rubber derivative, Bromobutyl Rubber Stoppers also have excellent resistance to weathering, ozone, and hot air; very good resistance to acidic and basic chemicals; very low permeability to gases and liquids; very good rheological properties, which can keep the stability of drug quality and the long-term preservation of the drug.
Compared to butyl rubber, Bromobutyl Rubber has a enhanced adhesion and faster cures. 
Medical Grade Silicone Rubber Stoppers are also widely used in medical Pharmaceutical sealing, like Antibiotics, bio-pharmaceutical, spray drug and infusion.
Compared to silicone rubber stoppers, Bromobutyl Rubber stoppers have better stability, longer life span and lower permeability to gases and liquid.
Besides, for a certain pharmaceutical, Bromobutyl Rubber stoppers have higher cleanliness, such as, Amino acid infusion and preparations. Bromobutyl Rubber stoppers are more often recommended.
Bromobutyl Rubber Stoppers Properties and Benefits
Low permeability
Cure versatility
Faster cure rate
Cure compatibility
Good adhesion
Better heat resistance
Good bio-safety
Bromobutyl Stoppers and
chlorobutyl rubbrers stoppers are both commonly used in medicine vials and bottles sealing. Compared with chlorobutyl rubbrers stoppers, Bromobutyl Rubber Stoppers have advantages and disadvantages as following:
Bromobutyl Stoppers- advantages:
a. Better stability and longer life span
b. More available vulcanization systems and higher cleanliness
Like polyamine vulcanization, during vulcanization process, It can avoid existence of harmful substance, such as sulfur (accelerant containing sulfur) and zinc oxide, ensuring higher cleanliness of stoppers and then reducing pollution and side-effects on pharmaceutical.
Bromobutyl Rubber Stoppers- disadvantages:
a. There exist a terrible smell during high temperature sterilization.
Bromobutyl Rubber Stoppers generally adopt sulfur vulcanization system, so heat resistance is worse slightly. Due to bromine element is relatively active, stoppers throw off a terrible smell during high temperature sterilization.
b. There is a greater influence in Hemolysis experiment
During Sulfur vulcanization, bromobutyl Rubber Stoppers need to add a accelerating vulcanizing agents, which has influence on stopper’s Hemolysis experiment.
Xiamen Better Silicone Import and Export Company is specialized in mold-making (since 1998) and production of
Bromobutyl Rubber Stoppers according to customer’s 2D/3D designed drawings or samples. Therefore, we have rich experience and in-depth expertise in applications of bromobutyl Rubber stoppers for sealing medicine vials and bottles. We make three mold plates to avoid parting line on stopper’s surface for better sealing effect.